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In the last column we met scientists Joan Strassmann and Pierre Stallforth, and left Joan, lying on the ground in a Virginia forest, peering through a magnifying glass at a pile of steaming deer scat. She saw the first Dictyostelium fruiting body in the wild, sprouting out of a pellet of poop.
The title of a recent paper in the Journal of the American Chemical Society, or JACS for short, is: Ecological Niche-Inspired Genome Mining Leads to the Discovery of Crop-Protecting Non-ribosomal Lipopeptides Featuring a Transient Amino Acid Building Block. JACS publishes heavy stuff.
The U.S. Energy Department has reported that the Chinese scientists did not make the Wuhan-1 version (as it was then called) of the SARS-Cov-2 coronavirus. This conclusion is the most important, but least remarked. Virologists, Chinese or American, would not have known how to create such a virus.
Every year, on the weekend before Labor Day, the Norfolk Library holds its book sale. On Sunday, after 12,000 books have been picked over, oddities appear. Early Connecticut Probate Court Records, Vol. I Hartford District, 1635-1700, a record printed in the 1890’s was one such book.
Pandemics leave their remnants in traumas of death and illness. Nurses, doctors, and patients were stunned by the scrambles that the Covid-19 virus produced. Columbia Presbyterian, a thousand bed teaching hospital in Manhattan was converted to emergency rooms to treat gasping Covid patients.
Many years ago, never mind how many, a biology student from Manila wrote to me about earning a PhD at Columbia University. At the time, I was head of the PhD program in the Department of Anatomy and Cell Biology at the Columbia University Irving Medical Center.
What have the scientific, pharmaceutical, and medical communities done to stifle SARS-CoV-2 infections? There are currently 18 advanced trials of different vaccines, 64 possible new treatments, and 23 potential or approved anti-viral drugs.
Afew months ago, we were enjoying the reopening of civil society. But events intervened. First, the protection of two-dose vaccines started to subside. Second, unvaccinated patients, including children, were sickened by the furiously infectious omicron variant of SARS-CoV-2.
In an extraordinary 20 months, science has tackled the SARS-CoV-2 virus and made vaccines for adults and children. Scientists have developed monoclonal antibodies that help if given early; we now have the first drugs that could stop infections or tilt the immunological fight in favor of the patient.
My wife does not like clutter. When she sees 50 issues of Nature, the British science magazine, piled on my desk, she gets a little peremptory. Out! she said. I decided on the dignity of an orderly retreat. I had been looking for subjects to write about in what I hope will be a post-COVID world. Call it an act of faith, or at least optimism.
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